4-(4-[(1s)(4-chlorophenyl)-2-pyridylmethoxy]piperidyl)butanoic acid - Names and Identifiers
4-(4-[(1s)(4-chlorophenyl)-2-pyridylmethoxy]piperidyl)butanoic acid - Physico-chemical Properties
4-(4-[(1s)(4-chlorophenyl)-2-pyridylmethoxy]piperidyl)butanoic acid - Introduction
()-(S)-4-[4-[1-(4-Chloroph-enyl)-1-(2-pyridyl)Methoxy]pip-eridin-1-yl]butyric acid is a chiral organic compound, the chemical formula is C19H22ClNO3.
Nature:
( )-(S)-4-[4-[1-(4-Chloroph-enyl)-1-(2-pyridyl)Methoxy]pip-eridin-1-yl]butyric acid is a colorless crystalline solid, it is a mixture with mirror image isomers. It has the structure of an oxalate ester, which contains functional groups such as the amino acids butyric acid and piperidine.
Use:
This compound is an important chiral intermediate, which is widely used in the preparation of drugs and pharmaceutical active ingredients in organic synthesis. It can be used as a synthetic raw material for antibiotics, analgesics and anti-inflammatory drugs.
Method:
A common preparation method is to prepare ()-(S)-4-[4-[1-(4-Chloroph-enyl) by synthesizing the substituted product of piperidine -1-(2-pyridyl)Methoxy]pip-eridin-1-yl]butyric acid. The specific synthesis method includes using benzoic acid as raw material to prepare 4-chlorobenzoic acid, then reacting with piperidine, plus sodium hydride, oxidant and other reagents to obtain the target product.
Safety Information:
The safety of ()-(S)-4-[4-[1-(4-Chloroph-enyl)-1-(2-pyridyl)Methoxy]pip-eridin-1-yl]butyric acid requires further evaluation. During handling and handling, appropriate laboratory safety measures should be taken, such as wearing chemical protective gloves, protective glasses and protective face masks. In high temperature, high pressure or contact with strong oxidizing agents, it may produce dangerous chemical reactions.
Last Update:2024-04-09 02:00:43